急性高甘油三酯血症胰腺炎康复期多学科管理专家共识
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浙江省2025年度“尖兵领雁+X”科技计划基金资助项目(2025C02180);2022年浙江省卫生高层次人才培养项目基金资助项目。


Expert consensus on multidisciplinary management in the recovery period of acute hypertriglyceridemic pancreatitis
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    摘要:

    急性高甘油三酯血症胰腺炎发病率逐年上升,复发率高,严重影响患者长期预后。目前相关指南主要集中在急性期治疗,康复期缺乏规范化管理。为弥补这一不足,浙江省预防医学会联合全国多学科专家,基于循证医学证据与临床实践经验,制定本专家共识。共识重点围绕病因识别与复发风险评估、血清甘油三酯控制目标、生活方式与药物干预、营养与微生态管理、并发症及合并症防治、心理与中医干预,以及随访和多学科团队模式应用等方面,提出可操作的推荐意见。旨在为临床提供规范化、个体化管理路径,降低复发风险,改善患者长期结局。

    Abstract:

    The incidence of acute hypertriglyceridemic pancreatitis (HTG-AP) has been rising, with high recurrence and poor long-term outcomes. Current guidelines mainly address the acute phase, leaving a gap in standardized recovery-phase management. To fill this gap, the Zhejiang Provincial Preventive Medicine Association, together with multidisciplinary experts nationwide, developed this consensus based on evidence and clinical practice. The document highlights key aspects including etiology identification and recurrence risk assessment, triglyceride control targets, lifestyle and pharmacologic interventions, nutritional and gut microbiota management, prevention of complications and comorbidities, psychological and traditional Chinese medicine interventions, as well as structured follow-up and multidisciplinary team care. Practical recommendations are proposed to standardize and individualize management during recovery, aiming to reduce recurrence risk and improve long-term outcomes in patients with HTG-AP.

    图1 HTG-AP康复期患者管理流程图Fig.1 Flowchart for the management of HTG-AP patients in the recovery period
    表 1 循证证据等级Table 1 Level of evidence
    表 2 临床推荐分级Table 2 Clinical recommendation grading
    表 3 常用降低甘油三酯药物Table 3 Commonly used drugs for lowering triglycerides
    表 4 新型降脂药物及作用靶点Table 4 New lipid-lowering drugs and their target sites
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.急性高甘油三酯血症胰腺炎康复期多学科管理专家共识[J].中国普通外科杂志,2025,34(9):1842-1857.
DOI:10.7659/j. issn.1005-6947.250522

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  • 收稿日期:2025-09-16
  • 最后修改日期:2025-09-18
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  • 在线发布日期: 2025-10-29