砥砺奋进,再创辉煌—中国甲状腺肿瘤学科20年发展与方向
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作者单位:

1.天津市人民医院/南开大学第一附属医院 乳腺甲状腺外科,天津 300121;2.天津医科大学肿瘤医院 甲状腺颈部肿瘤科/国家恶性肿瘤临床医学研究中心/天津市恶性肿瘤临床医学研究中心/天津市肿瘤防治重点实验室,天津 300060

作者简介:

高明,天津市人民医院/南开大学第一附属医院主任医师,主要从事甲状腺肿瘤基础与转化研究方面的研究。

基金项目:

国家自然科学基金资助项目(82372753)。


Striving forward to create new glory—20 years of development and future directions in the field of thyroid tumors in China
Author:
Affiliation:

1.Department of Thyroid and Breast Surgery, Tianjin Union Medical Center, the First Affiliated Hospital of Nankai University, Tianjin 300121, China;2.Department of Thyroid and Neck Oncology, Tianjin Medical University Cancer Institute and Hospital/National Clinical Research Center for Cancer/Tianjin Clinical Research Center for Cancer/Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China

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    摘要:

    在过去的20年间,中国甲状腺肿瘤学科经历了迅猛的发展,通过规范化进程的完善、治疗手段的不断创新以及基础研究的深入,甲状腺癌5年生存率从67.5%显著提升至92.9%。在诊断领域,彩超诊断技术的提升、TI-RADS分级标准的建立以及细针穿刺诊断模式的革新,特别是分子诊断的加入,极大地提高了术前诊断的准确率。在治疗方面,逐步从传统手术向个体化精准治疗转变,结合放射性碘治疗、内分泌调控、靶向及免疫治疗,形成了多学科综合诊疗体系,为患者提供了更为精准和有效的治疗方案。晚期甲状腺癌的治疗手段也取得了显著进步,靶向药物的应用为患者带来了新的治疗希望。在研究领域,中国学者在甲状腺癌领域的文献发表量大幅增长,高水平研究不断涌现,彰显了我国在该领域的迅速崛起。同时,学术组织的成立与专业指南的推广,也极大地促进了基层医生诊疗水平的提升。展望未来,我们将继续致力于新一代靶向药物的研发、人工智能及智能决策系统在诊疗中的应用、基于大数据的预后预测模型的构建以及5G+远程医疗的普及,推动甲状腺肿瘤学科向更加精准、微创和个体化的方向发展,再创辉煌。

    Abstract:

    Over the past two decades, the field of thyroid oncology in China has undergone rapid development. Through improvements in standardization processes, continuous innovations in treatment methods, and in-depth basic research, the 5-year survival rate of thyroid cancer has significantly increased from 67.5% to 92.9%. In diagnostics, advancements in color Doppler ultrasound technology, the establishment of the TI-RADS classification system, and innovations in fine-needle aspiration biopsy methods, particularly the integration of molecular diagnostics, have greatly improved the accuracy of preoperative diagnosis. In terms of treatment, there has been a gradual shift from traditional surgery to individualized precision therapy. Combined with radioactive iodine therapy, endocrine regulation, targeted therapy, and immunotherapy, a multidisciplinary comprehensive diagnosis and treatment system has been formed, providing patients with more precise and effective treatment options. Significant progress has also been made in the treatment of advanced thyroid cancer, with the application of targeted drugs bringing new hope to patients. In research, Chinese scholars have greatly increased their publications in the field of thyroid cancer, with high-quality studies emerging continuously, reflecting China's rapid rise in this area. Meanwhile, the establishment of academic organizations and the promotion of professional guidelines have substantially enhanced the diagnostic and treatment capabilities of primary care physicians. Looking ahead, efforts will continue to focus on the development of next-generation targeted drugs, the application of artificial intelligence and intelligent decision-making systems in diagnosis and treatment, the construction of prognosis prediction models based on big data, and the popularization of 5G-enabled remote medical care. These advances will drive the development of thyroid oncology toward more precise, minimally invasive, and personalized directions, creating new brilliance once again.

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高明,李大鹏.砥砺奋进,再创辉煌—中国甲状腺肿瘤学科20年发展与方向[J].中国普通外科杂志,2025,34(5):837-841.
DOI:10.7659/j. issn.1005-6947.250205

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  • 收稿日期:2025-04-14
  • 最后修改日期:2025-05-24
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  • 在线发布日期: 2025-07-01