DCD供肝全肝移植中变异肝动脉的评估和处理现状
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宁波大学附属李惠利医院 肝胆胰外科,浙江 宁波 315048

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俞琪,宁波大学附属李惠利医院硕士研究生,主要从事肝胆胰方面的研究。

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2024年度市公益性研究计划基金资助项目(2024S155); 2024年度宁波市医疗卫生高端团队重大攻坚基金资助项目(2024020818);2024年市重点技术研发基金资助项目(2024Z179)。


Current status of assessment and management of variant hepatic arteries in DCD liver transplantation
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Department of Hepatobiliary and Pancreatic Surgery, Li Huili Hospital, Affiliated with Ningbo University, Ningbo, Zhejiang 315048, China

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    摘要:

    心脏死亡捐献供肝全肝移植(DCD-LT)是终末期肝病的根治性治疗手段,但肝动脉解剖变异在移植中十分常见,若处理不当可导致供肝局部供血不足及移植物功能障碍。如何精准处理变异肝动脉仍是手术成功的关键难点。本文综述了基于Michels等分型的多种解剖学分类体系,阐述了影像学技术在DCD-LT中对变异肝动脉的评估及术中决策价值,并总结了外科手术的主要处理方式。重点探讨了复杂变异动脉重建的标准化策略,并提出未来研究方向,以期为DCD-LT中变异肝动脉的评估和处理提供参考。

    Abstract:

    Donation after circulatory death liver transplantation (DCD-LT) remains a curative treatment for end-stage liver disease. Variant hepatic arteries are frequently encountered during transplantation, and inadequate management may result in localized ischemia and graft dysfunction. Precise handling of these variations remains a critical determinant of surgical success. This review summarizes anatomical classifications based on Michels' typology, highlights the value of imaging modalities in preoperative evaluation and intraoperative decision-making, and outlines current surgical approaches. Particular emphasis is placed on standardized strategies for arterial reconstruction in complex variations. Future research perspectives are also proposed, aiming to optimize assessment and management of variant hepatic arteries in DCD-LT.

    图1 Michels变异分型 A:正常肝动脉解剖;B:rLHA、rRHA可能单独或同时存在;C-D:单独的rLHA、rRHA 注:GDA为胃十二指肠动脉;LHA为肝左动脉;RHA为肝右动脉Fig.1 Michels classification of hepatic artery variations A: Normal hepatic artery anatomy; B: rLHA and rRHA may occur alone or simultaneously; C-D: Isolated rLHA or rRHA Note: GDA, gastroduodenal artery; LHA, left hepatic artery; RHA, right hepatic artery
    图2 Hiatt变异分型 A:正常亚型;B:a/rLHA由LGA分支;C:a/rRHA由SMA分支;D:为双替代型,RHA发自SMA且LHA发自LGA;E:CHA起源于SMA,部分发自其他部位的变异类型构成第6型Fig.2 Hiatts classification of hepatic artery variations A: Normal subtype; B: a/rLHA originating from LGA; C: a/rRHA originating from SMA; D: Double replacement type, with RHA arising from SMA and LHA from LGA; E: CHA originating from SMA, with other rare variants included in type Ⅵ
    图3 Soin肝动脉重建方式(A-E说明见表3) 注:D-代表供体,R-代表受体;HA代表肝动脉Fig.3 Soins methods of hepatic artery reconstruction (A-E as described in Table 3) Note: D-represents donor, R-represents recipient; HA, hepatic artery
    图4 变异肝动脉重建方式(A-L说明见表4) 注:D-代表供体,R-代表受体;GDA为胃十二指肠动脉Fig.4 Reconstruction methods for variant hepatic arteries (A-L as described in Table 4) Note: D-represents donor, R-represents recipient; GDA, gastroduodenal artery
    表 1 变异肝动脉Michels及Hiatt分型Table 1 Classification of variant hepatic arteries according to Michels and Hiatt
    表 2 变异肝动脉Soin及Gruttadauria分型Table 2 Classification of variant hepatic arteries by Soin and Gruttadauri
    表 3 变异肝动脉Soin重建方式Table 3 Reconstruction methods for variant hepatic arteries reported by Soin
    表 4 变异肝动脉及重建方式Table 4 Variant hepatic arteries and reconstruction methods
    表 5 Table 5
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俞琪,房炯泽. DCD供肝全肝移植中变异肝动脉的评估和处理现状[J].中国普通外科杂志,2025,34(8):1766-1776.
DOI:10.7659/j. issn.1005-6947.250175

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  • 收稿日期:2025-03-25
  • 最后修改日期:2025-08-21
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  • 在线发布日期: 2025-10-11