肝癌转化治疗临床应用中的共识和争议
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国家癌症中心/国家肿瘤临床研究中心/中国医学科学院北京协和医学院肿瘤医院 肝胆外科,北京 100021

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魏哲文收集文献资料、总结撰写文章;毕新宇提供文章思路、审阅并修改文章。

基金项目:

中国医学科学院医学与健康科技创新工程基金资助项目(2021-I2M-1-066);广东省深圳市“医疗卫生三名工程”基金资助项目(SZSM202011010)。


Consensus and controversies in the clinical application of translational therapy for liver cancer
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Department of Hepatobiliary Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China

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    摘要:

    肝癌转化治疗作为一种新兴的治疗策略,正在推动中晚期肝癌治疗的进步。经过全国专家的不断探索,肝癌转化治疗已经形成了相关共识,为临床实践提供了宝贵的科学指导。然而,随着治疗方法的不断更新,转化治疗仍面临许多亟待解决的挑战,尤其是在个体化治疗、疗效评估、联合治疗策略等方面的难题。这些问题已经成为当下具有争议性的热点话题,形成了“共识与争议同在,机遇与挑战并存”的局面。要解决这些问题,肝癌领域的专家们需要加强合作与交流,推动高质量的基础与临床研究,并在实践中不断改进治疗方案,以便为患者提供更加科学和精准的治疗方案。

    Abstract:

    Translational therapy for liver cancer, as an emerging treatment strategy, is driving advancements in the management of intermediate and advanced liver cancer. Through continuous exploration by experts nationwide, translational therapy for liver cancer has reached a consensus, providing valuable scientific guidance for clinical practice. However, as treatment methods continue to evolve, translational therapy still faces numerous urgent challenges, particularly in areas such as personalized treatment, efficacy evaluation, and combined therapeutic strategies. These issues have become contentious and hotly debated topics, creating a situation where "consensus and controversy coexist, and opportunities and challenges intersect." To address these challenges, experts in the field of liver cancer must strengthen collaboration and communication, promote high-quality basic and clinical research, and continuously refine treatment protocols in practice, ultimately offering patients more scientific and precise therapeutic options.

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魏哲文,毕新宇.肝癌转化治疗临床应用中的共识和争议[J].中国普通外科杂志,2025,34(1):47-53.
DOI:10.7659/j. issn.1005-6947.240626

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  • 收稿日期:2024-11-30
  • 最后修改日期:2025-01-12
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  • 在线发布日期: 2025-02-10