Abstract:Background and Aims Elderly patients undergoing laparoscopic radical resection of colon cancer often experience decreased sleep quality, which may hinder postoperative recovery. Although pharmacological interventions are commonly used in clinical practice to improve postoperative sleep, conventional medications may lead to adverse effects such as delirium and dependence. This study aimed to evaluate the effect of a non-pharmacological intervention—buccal acupuncture combined with ultrasound-guided stellate ganglion block (SGB)—on postoperative sleep quality in elderly patients.Methods A total of 60 elderly patients who underwent laparoscopic radical resection of colon cancer at the Forth Hospital of Changsha from February to August 2024 were enrolled. Using a random number table, the patients were divided into two groups: 30 in the control group (SGB alone) and 30 in the study group (SGB combined with buccal acupuncture). Perioperative mean arterial pressure (MAP), heart rate (HR), postoperative visual analogue scale (VAS) scores, Pittsburgh Sleep Quality Index (PSQI) scores, and the incidence of adverse events were recorded and analyzed.Results There were no statistically significant differences in baseline characteristics between the two groups (all P>0.05). The study group showed significantly lower intraoperative and postoperative HR and MAP compared to the control group (all P<0.05). VAS scores at 6, 24, and 48 h postoperatively, as well as PSQI scores on postoperative days 1, 3, and 5, were significantly lower in the study group (all P<0.05). Additionally, the incidence of drowsiness was significantly reduced (P<0.05). No significant differences were found between the two groups in terms of nausea, vomiting, or agitation (all P>0.05).Conclusion The combination of buccal acupuncture and SGB during the perioperative period can effectively improve postoperative sleep quality, alleviate pain, and reduce adverse reactions in elderly patients undergoing laparoscopic radical resection of colon cancer. This safe and effective non-pharmacological intervention holds promising clinical application value.