胰十二指肠切除术后患者腹泻71例分析

Analysis of post-pancreatoduodenectomy diarrhea: a report of 71 cases

摘要:

目的： 分析胰十二指肠切除术后患者腹泻发生的原因及机制，并探讨治疗对策。方法：以笔者近1年半内收治的159例胰十二指肠切除术患者为对象，分析术后腹泻发生的原因及不同的处理方法。结果：全组有71例发生不同程度的腹泻，发生率为44.7％。其中22例为肠道细菌感染，4例出现真菌感染，感染发生率占腹泻患者的36.6%。针对不同的病因给予治疗后，64例腹泻有不同程度的缓解，有效率为90.1％；7例出现慢性腹泻，经一般治疗效果不明显者，加用口服胰酶片治疗，2周后腹泻较用药前有明显缓解。 结论：腹泻在胰十二指肠切除术后患者中较多见，根据不同的病因进行相应处理多能治愈。

Abstract:

Abstract:Objective：To explore the etiology, mechanism and treatment of diarrhea after pancreatoduodenectomy. Methods：Based on the clinical data of 159 cases of pancreatoduodenectomy performed in the recent one and half years, the pathogenesis of post-pancreatoduodenectomy diarrhea was analyzed and the effect of different treatments was observed. Results：Seventy-one cases had diarrhea, with an incidence of 44.7%. Tweenty-two cases had bacterial infection of the intestinal tract and 4 cases had fungus infection. The incidence of infection was 36.6%. In 64 cases diarrhea was relieved with effective treatment, accounting for 90.1% of all cases. Seven cases with chronic diarrhea had additional treatment with oral pancreatic enzyme and symptoms were relieved 2 weeks after treatment. Conclusions：Diarrhea is frequently observed in patients after pancreatoduodenectomy, and the majority of them can be cured with treatment selected according to the pathogenesis.