Abstract:Hepatectomy has become the most important treatment method for hepatobiliary diseases. The perioperative management of hepatectomy is closely related to its safety and efficacy. Perioperative management includes systematic evaluation and management of the patient′s condition before, during, and after surgery, and its principles and methods have developed rapidly in recent years. In 2017, the Group of Liver Surgery of Surgical Society of Chinese Medical Association released the "Expert consensus on perioperative management of hepatectomy". On this basis, the editorial committee has reviewed existing evidence-based medicine research evidence, combined with the latest clinical practice experience of numerous liver surgery centers at home and abroad, organized a multidisciplinary expert team in relevant fields in China for discussion, and revised to formulate the Guidelines for multidisciplinary clinical management of perioperative period of hepatectomy (2025 edition). This guideline covers a systematic assessment, treatment principles, and methods for relevant conditions before, during, and after hepatectomy, and provides specific recommendations. The revision of the guidelines aims to promote the standardization and refinement of clinical practice in this field, improve the safety and clinical efficacy of liver resection, and provide guidance and reference for clinical professionals related to liver surgery.